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【参考資料２－３】抗微生物薬適正使用の手引き 第四版（案）薬剤耐性菌感染症の抗菌薬適正使用編 (98 ページ)
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抗微生物薬適正使用の手引き
第四版
薬剤耐性菌感染症の抗菌薬適正使用編
1
2
3
4
151. Lasko MJ, et al. In Vitro Time-Kill Studies of Trimethoprim/Sulfamethoxazole against
Stenotrophomonas maltophilia versus Escherichia coli Using Cation-Adjusted MuellerHinton Broth and ISO-Sensitest Broth. Antimicrob Agents Chemother. 2022.
66(3):e0216721.
5
6
7
152. Lasko MJ, et al. Trimethoprim/sulfamethoxazole pharmacodynamics against
Stenotrophomonas maltophilia in the in vitro chemostat model. J Antimicrob Chemother.
2022. 77(11):3187-3193.
8
9
10
153. Wang YL, et al. Monotherapy with fluoroquinolone or trimethoprim-sulfamethoxazole for
treatment of Stenotrophomonas maltophilia infections. Antimicrob Agents Chemother.
2014. 58(1):176-82.
11
12
13
154. Watson L, et al. Sulfamethoxazole/trimethoprim versus fluoroquinolones for the
treatment of Stenotrophomonas maltophilia bloodstream infections. J Glob Antimicrob
Resist. 2018. 12:104-106.
14
15
16
155. Nys C, et al. Clinical and Microbiologic Outcomes in Patients with Monomicrobial
Stenotrophomonas maltophilia Infections. Antimicrob Agents Chemother. 2019.
63(11):e00788-19.
17
18
19
156. Junco SJ, et al. Clinical outcomes of Stenotrophomonas maltophilia infection treated
with trimethoprim/sulfamethoxazole, minocycline, or fluoroquinolone monotherapy. Int J
Antimicrob Agents. 2021. 58(2):106367.
20
21
22
157. Almangour TA, et al. Trimethoprim-sulfamethoxazole versus levofloxacin for the
treatment of Stenotrophomonas maltophilia infections: A multicentre cohort study. J Glob
Antimicrob Resist. 2024. 38:42-48.
23
24
25
158. Cho SY, et al. Can levofloxacin be a useful alternative to trimethoprim-sulfamethoxazole
for treating Stenotrophomonas maltophilia bacteremia? Antimicrob Agents Chemother.
2014. 58(1):581-583.
26
27
28
159. Ko JH, et al. Fluoroquinolones versus trimethoprim-sulfamethoxazole for the treatment
of Stenotrophomonas maltophilia infections: a systematic review and meta-analysis. Clin
Microbiol Infect. 2019. 25(5):546-554.
29
30
31
32
160. Sarzynski SH, et al. Trimethoprim-Sulfamethoxazole Versus Levofloxacin for
Stenotrophomonas maltophilia Infections: A Retrospective Comparative Effectiveness
Study of Electronic Health Records from 154 US Hospitals. Open Forum Infect Dis.
2022. 9(2):ofab644.
33
34
35
161. Alhayani T, et al. Comparison of Doxycycline or Minocycline to SulfamethoxazoleTrimethoprim for Treatment of Stenotrophomonas maltophilia Pneumonia. Ann
Pharmacother. 2024. 58(1):21-27.
36
37
38
162. Graves ET, et al. Comparison of trimethoprim-sulfamethoxazole versus minocycline
monotherapy for treatment of Stenotrophomonas maltophilia pneumonia. J Antimicrob
Chemother. 2025. 80(4):988-995.
39
40
41
163. Hand E, et al. Monotherapy with minocycline or trimethoprim/sulfamethoxazole for
treatment of Stenotrophomonas maltophilia infections. J Antimicrob Chemother. 2016.
71(4):1071-1075.
42
43
164. Tekçe YT, et al. Tigecycline as a therapeutic option in Stenotrophomonas maltophilia
infections. J Chemother. 2012. 24(3):150-4.
44
45
46
165. Zha L, et al. Tigecycline in the Treatment of Ventilator-Associated Pneumonia Due to
Stenotrophomonas maltophilia: A Multicenter Retrospective Cohort Study. Infect Dis
Ther. 2021. 10(4):2415-2429.
98
第四版
薬剤耐性菌感染症の抗菌薬適正使用編
1
2
3
4
151. Lasko MJ, et al. In Vitro Time-Kill Studies of Trimethoprim/Sulfamethoxazole against
Stenotrophomonas maltophilia versus Escherichia coli Using Cation-Adjusted MuellerHinton Broth and ISO-Sensitest Broth. Antimicrob Agents Chemother. 2022.
66(3):e0216721.
5
6
7
152. Lasko MJ, et al. Trimethoprim/sulfamethoxazole pharmacodynamics against
Stenotrophomonas maltophilia in the in vitro chemostat model. J Antimicrob Chemother.
2022. 77(11):3187-3193.
8
9
10
153. Wang YL, et al. Monotherapy with fluoroquinolone or trimethoprim-sulfamethoxazole for
treatment of Stenotrophomonas maltophilia infections. Antimicrob Agents Chemother.
2014. 58(1):176-82.
11
12
13
154. Watson L, et al. Sulfamethoxazole/trimethoprim versus fluoroquinolones for the
treatment of Stenotrophomonas maltophilia bloodstream infections. J Glob Antimicrob
Resist. 2018. 12:104-106.
14
15
16
155. Nys C, et al. Clinical and Microbiologic Outcomes in Patients with Monomicrobial
Stenotrophomonas maltophilia Infections. Antimicrob Agents Chemother. 2019.
63(11):e00788-19.
17
18
19
156. Junco SJ, et al. Clinical outcomes of Stenotrophomonas maltophilia infection treated
with trimethoprim/sulfamethoxazole, minocycline, or fluoroquinolone monotherapy. Int J
Antimicrob Agents. 2021. 58(2):106367.
20
21
22
157. Almangour TA, et al. Trimethoprim-sulfamethoxazole versus levofloxacin for the
treatment of Stenotrophomonas maltophilia infections: A multicentre cohort study. J Glob
Antimicrob Resist. 2024. 38:42-48.
23
24
25
158. Cho SY, et al. Can levofloxacin be a useful alternative to trimethoprim-sulfamethoxazole
for treating Stenotrophomonas maltophilia bacteremia? Antimicrob Agents Chemother.
2014. 58(1):581-583.
26
27
28
159. Ko JH, et al. Fluoroquinolones versus trimethoprim-sulfamethoxazole for the treatment
of Stenotrophomonas maltophilia infections: a systematic review and meta-analysis. Clin
Microbiol Infect. 2019. 25(5):546-554.
29
30
31
32
160. Sarzynski SH, et al. Trimethoprim-Sulfamethoxazole Versus Levofloxacin for
Stenotrophomonas maltophilia Infections: A Retrospective Comparative Effectiveness
Study of Electronic Health Records from 154 US Hospitals. Open Forum Infect Dis.
2022. 9(2):ofab644.
33
34
35
161. Alhayani T, et al. Comparison of Doxycycline or Minocycline to SulfamethoxazoleTrimethoprim for Treatment of Stenotrophomonas maltophilia Pneumonia. Ann
Pharmacother. 2024. 58(1):21-27.
36
37
38
162. Graves ET, et al. Comparison of trimethoprim-sulfamethoxazole versus minocycline
monotherapy for treatment of Stenotrophomonas maltophilia pneumonia. J Antimicrob
Chemother. 2025. 80(4):988-995.
39
40
41
163. Hand E, et al. Monotherapy with minocycline or trimethoprim/sulfamethoxazole for
treatment of Stenotrophomonas maltophilia infections. J Antimicrob Chemother. 2016.
71(4):1071-1075.
42
43
164. Tekçe YT, et al. Tigecycline as a therapeutic option in Stenotrophomonas maltophilia
infections. J Chemother. 2012. 24(3):150-4.
44
45
46
165. Zha L, et al. Tigecycline in the Treatment of Ventilator-Associated Pneumonia Due to
Stenotrophomonas maltophilia: A Multicenter Retrospective Cohort Study. Infect Dis
Ther. 2021. 10(4):2415-2429.
98