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【参考資料２－３】抗微生物薬適正使用の手引き 第四版（案）薬剤耐性菌感染症の抗菌薬適正使用編 (47 ページ)
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抗微生物薬適正使用の手引き
第四版
薬剤耐性菌感染症の抗菌薬適正使用編
1
2
3
18. Prematunge C, et al. VRE and VSE Bacteremia Outcomes in the Era of Effective VRE
Therapy: A Systematic Review and Meta-analysis. Infect Control Hosp Epidemiol. 2016.
37:26-35.
4
5
19. 日本化学療法学会 抗菌化学療法認定医認定制度審議委員会 抗菌薬適正使用生涯教育テ
キスト 第 3 版 2020.
6
20. 富田治芳, 他. バンコマイシン耐性腸球菌. 日臨微誌. 2014. 24(3):10-24.
7
8
9
10
11
12
13
21. Wurpts G, et al. Guideline on diagnostic procedures for suspected hypersensitivity to βlactam antibiotics: Guideline of the German Society for Allergology and Clinical
Immunology (DGAKI) in collaboration with the German Society of Allergology (AeDA),
German Society for Pediatric Allergology and Environmental Medicine (GPA), the
German Contact Dermatitis Research Group (DKG), the Austrian Society for Allergology
and Immunology (OGAI), and the Paul-Ehrlich Society for Chemotherapy (PEG). Allergol
Select. 2020. 4:11-43.
14
15
16
22. Baddour LM, et al. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy,
and Management of Complications: A Scientific Statement for Healthcare Professionals
From the American Heart Association. Circulation. 2015. 132(15):1435-1486.
17
18
19
23. Britt NS, et al. Comparison of the Effectiveness and Safety of Linezolid and Daptomycin
in Vancomycin-Resistant Enterococcal Bloodstream Infection: A National Cohort Study
of Veterans Affairs Patients. Clin Infect Dis. 2015. 61(6):871-878.
20
21
24. Paterson DL, et al. Extended-spectrum β-lactamases: a clinical update. Clin Microbiol
Rev. 2005. 18(4):657-686.
22
23
25. Castanheira M, et al. Extended-spectrum β-lactamases: an update on their
characteristics, epidemiology and detection. JAC Antimicrob Resist. 2021. 3(3):dlab092.
24
25
26. JANIS 公開情報 院内感染対策サーベイランス 検査部門 入院検体. 2023. at
https://janis.mhlw.go.jp/report/open_report/2023/3/1/ken_Open_Report_202300.pdf
26
27
28
27. JANIS 公開情報 院内感染対策サーベイランス 検査部門 外来検体. 2023. at
https://janis.mhlw.go.jp/report/open_report/2023/3/1/ken_Open_Report_202300_Outpati
ent.pdf
29
30
31
28. Arcilla MS, et al. Import and spread of extended-spectrum β-lactamase-producing
Enterobacteriaceae by international travellers (COMBAT study): a prospective,
multicentre cohort study. Lancet Infect Dis. 2017. 17(1):78-85.
32
33
34
29. Rodriguez-Bano J, et al. Community-onset bacteremia due to extended-spectrum βlactamase-producing Escherichia coli: risk factors and prognosis. Clin Infect Dis. 2010.
50(1):40-48.
35
36
37
30. Goodman KE, et al. A Clinical Decision Tree to Predict Whether a Bacteremic Patient Is
Infected With an Extended-Spectrum β-Lactamase-Producing Organism. Clin Infect Dis.
2016. 63(7):896-903.
38
39
31. CLSI. Performance Stadards for Antimicrobial Susceptibility Testing. 35th ed. CLSI
supplement M100. Clinical and Laboratory Standards Institute; 2025.
40
41
32. 一般社団法人日本臨床微生物学会 多剤耐性菌検査の手引き. 2021. at
https://www.jscm.org/modules/guideline/index.php?content_id=15.)
42
43
44
33. Nicolle LE, et al. Clinical Practice Guideline for the Management of Asymptomatic
Bacteriuria: 2019 Update by the Infectious Diseases Society of America. Clin Infect Dis.
2019. 68(10):e83-e110.
47
第四版
薬剤耐性菌感染症の抗菌薬適正使用編
1
2
3
18. Prematunge C, et al. VRE and VSE Bacteremia Outcomes in the Era of Effective VRE
Therapy: A Systematic Review and Meta-analysis. Infect Control Hosp Epidemiol. 2016.
37:26-35.
4
5
19. 日本化学療法学会 抗菌化学療法認定医認定制度審議委員会 抗菌薬適正使用生涯教育テ
キスト 第 3 版 2020.
6
20. 富田治芳, 他. バンコマイシン耐性腸球菌. 日臨微誌. 2014. 24(3):10-24.
7
8
9
10
11
12
13
21. Wurpts G, et al. Guideline on diagnostic procedures for suspected hypersensitivity to βlactam antibiotics: Guideline of the German Society for Allergology and Clinical
Immunology (DGAKI) in collaboration with the German Society of Allergology (AeDA),
German Society for Pediatric Allergology and Environmental Medicine (GPA), the
German Contact Dermatitis Research Group (DKG), the Austrian Society for Allergology
and Immunology (OGAI), and the Paul-Ehrlich Society for Chemotherapy (PEG). Allergol
Select. 2020. 4:11-43.
14
15
16
22. Baddour LM, et al. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy,
and Management of Complications: A Scientific Statement for Healthcare Professionals
From the American Heart Association. Circulation. 2015. 132(15):1435-1486.
17
18
19
23. Britt NS, et al. Comparison of the Effectiveness and Safety of Linezolid and Daptomycin
in Vancomycin-Resistant Enterococcal Bloodstream Infection: A National Cohort Study
of Veterans Affairs Patients. Clin Infect Dis. 2015. 61(6):871-878.
20
21
24. Paterson DL, et al. Extended-spectrum β-lactamases: a clinical update. Clin Microbiol
Rev. 2005. 18(4):657-686.
22
23
25. Castanheira M, et al. Extended-spectrum β-lactamases: an update on their
characteristics, epidemiology and detection. JAC Antimicrob Resist. 2021. 3(3):dlab092.
24
25
26. JANIS 公開情報 院内感染対策サーベイランス 検査部門 入院検体. 2023. at
https://janis.mhlw.go.jp/report/open_report/2023/3/1/ken_Open_Report_202300.pdf
26
27
28
27. JANIS 公開情報 院内感染対策サーベイランス 検査部門 外来検体. 2023. at
https://janis.mhlw.go.jp/report/open_report/2023/3/1/ken_Open_Report_202300_Outpati
ent.pdf
29
30
31
28. Arcilla MS, et al. Import and spread of extended-spectrum β-lactamase-producing
Enterobacteriaceae by international travellers (COMBAT study): a prospective,
multicentre cohort study. Lancet Infect Dis. 2017. 17(1):78-85.
32
33
34
29. Rodriguez-Bano J, et al. Community-onset bacteremia due to extended-spectrum βlactamase-producing Escherichia coli: risk factors and prognosis. Clin Infect Dis. 2010.
50(1):40-48.
35
36
37
30. Goodman KE, et al. A Clinical Decision Tree to Predict Whether a Bacteremic Patient Is
Infected With an Extended-Spectrum β-Lactamase-Producing Organism. Clin Infect Dis.
2016. 63(7):896-903.
38
39
31. CLSI. Performance Stadards for Antimicrobial Susceptibility Testing. 35th ed. CLSI
supplement M100. Clinical and Laboratory Standards Institute; 2025.
40
41
32. 一般社団法人日本臨床微生物学会 多剤耐性菌検査の手引き. 2021. at
https://www.jscm.org/modules/guideline/index.php?content_id=15.)
42
43
44
33. Nicolle LE, et al. Clinical Practice Guideline for the Management of Asymptomatic
Bacteriuria: 2019 Update by the Infectious Diseases Society of America. Clin Infect Dis.
2019. 68(10):e83-e110.
47