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【参考資料２－２】抗微生物薬適正使用の手引き 第四版（案）医科・入院編 (52 ページ)
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抗微生物薬適正使用の手引き
第四版
医科・入院編
1
2
3
14. Kalil AC, et al. Management of Adults With Hospital-acquired and Ventilator-associated
Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of
America and the American Thoracic Society. Clin Infect Dis. 2016. 63(5):e61-e111.
4
5
6
7
15. Mo Y, et al. REGARD-VAP investigators. Individualised, short-course antibiotic treatment
versus usual long-course treatment for ventilator-associated pneumonia (REGARDVAP): a multicentre, individually randomised, open-label, non-inferiority trial. Lancet
Respir Med. 2024. 12(5):399-408.
8
9
10
11
16. Gupta K, et al. International clinical practice guidelines for the treatment of acute
uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious
Diseases Society of America and the European Society for Microbiology and Infectious
Diseases. Clin Infect Dis. 2011. 52(5):e103-20.
12
13
14
17. Hooton TM, et al. Diagnosis, prevention, and treatment of catheter-associated urinary
tract infection in adults: 2009 International Clinical Practice Guidelines from the
Infectious Diseases Society of America. Clin Infect Dis. 2010. 50(5):625-663.
15
16
17
18. McAteer J, et al. Defining the Optimal Duration of Therapy for Hospitalized Patients With
Complicated Urinary Tract Infections and Associated Bacteremia. Clin Infect Dis. 2023.
76(9):1604-1612.
18
19
20
19. Lafaurie M, et al. Antimicrobial for 7 or 14 Days for Febrile Urinary Tract Infection in Men:
A Multicenter Noninferiority Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
Clin Infect Dis. 2023. 76(12):2154-2162.
21
22
23
20. Cranendonk DR, et al. Antibiotic treatment for 6 days versus 12 days in patients with
severe cellulitis: a multicentre randomized, double-blind, placebo-controlled, noninferiority trial. Clin Microbiol Infect. 2020. 26(5):606-612.
24
25
26
21. Stevens DL, et al. Practice guidelines for the diagnosis and management of skin and
soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin
Infect Dis. 2014;59:e10-52.
27
28
22. JAID/JSC 感染症治療ガイド・ガイドライン作成委員会 JAID/JSC 感染症治療ガイド
2019. ライフサイエンス出版;2019
29
30
31
23. Mermel LA, et al. Clinical practice guidelines for the diagnosis and management of
intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society
of America. Clin Infect Dis. 2009. 49(1):1-45.
32
33
24. Gomi H, et al. Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and
cholecystitis. J Hepatobiliary Pancreat Sci. 2018. 25(1):3-16.
34
35
25. Haal S, et al. Antibiotic Therapy of 3 Days May Be Sufficient After Biliary Drainage for
Acute Cholangitis: A Systematic Review. Dig Dis Sci. 2021. 66(12):4128-4139.
36
37
26. Tinusz B, et al. Short-Course Antibiotic Treatment Is Not Inferior to a Long-Course One
in Acute Cholangitis: A Systematic Review. Dig Dis Sci. 2019. 64(2):307-315.
38
39
27. Sawyer RG, et al. Trial of short-course antimicrobial therapy for intraabdominal infection.
N Engl J Med. 2015. 372(21):1996-2005.
40
41
42
28. Solomkin JS, et al. Diagnosis and management of complicated intra-abdominal infection
in adults and children: guidelines by the Surgical Infection Society and the Infectious
Diseases Society of America. Clin Infect Dis. 2010. 50(2):133-164.
43
44
45
29. Molina J, et al. Seven-versus 14-day course of antibiotics for the treatment of
bloodstream infections by enterobacterales: a randomized, controlled trial: authors'
response. Clin Microbiol Infect. 2022. 28(5):739-740.
52
第四版
医科・入院編
1
2
3
14. Kalil AC, et al. Management of Adults With Hospital-acquired and Ventilator-associated
Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of
America and the American Thoracic Society. Clin Infect Dis. 2016. 63(5):e61-e111.
4
5
6
7
15. Mo Y, et al. REGARD-VAP investigators. Individualised, short-course antibiotic treatment
versus usual long-course treatment for ventilator-associated pneumonia (REGARDVAP): a multicentre, individually randomised, open-label, non-inferiority trial. Lancet
Respir Med. 2024. 12(5):399-408.
8
9
10
11
16. Gupta K, et al. International clinical practice guidelines for the treatment of acute
uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious
Diseases Society of America and the European Society for Microbiology and Infectious
Diseases. Clin Infect Dis. 2011. 52(5):e103-20.
12
13
14
17. Hooton TM, et al. Diagnosis, prevention, and treatment of catheter-associated urinary
tract infection in adults: 2009 International Clinical Practice Guidelines from the
Infectious Diseases Society of America. Clin Infect Dis. 2010. 50(5):625-663.
15
16
17
18. McAteer J, et al. Defining the Optimal Duration of Therapy for Hospitalized Patients With
Complicated Urinary Tract Infections and Associated Bacteremia. Clin Infect Dis. 2023.
76(9):1604-1612.
18
19
20
19. Lafaurie M, et al. Antimicrobial for 7 or 14 Days for Febrile Urinary Tract Infection in Men:
A Multicenter Noninferiority Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
Clin Infect Dis. 2023. 76(12):2154-2162.
21
22
23
20. Cranendonk DR, et al. Antibiotic treatment for 6 days versus 12 days in patients with
severe cellulitis: a multicentre randomized, double-blind, placebo-controlled, noninferiority trial. Clin Microbiol Infect. 2020. 26(5):606-612.
24
25
26
21. Stevens DL, et al. Practice guidelines for the diagnosis and management of skin and
soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin
Infect Dis. 2014;59:e10-52.
27
28
22. JAID/JSC 感染症治療ガイド・ガイドライン作成委員会 JAID/JSC 感染症治療ガイド
2019. ライフサイエンス出版;2019
29
30
31
23. Mermel LA, et al. Clinical practice guidelines for the diagnosis and management of
intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society
of America. Clin Infect Dis. 2009. 49(1):1-45.
32
33
24. Gomi H, et al. Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and
cholecystitis. J Hepatobiliary Pancreat Sci. 2018. 25(1):3-16.
34
35
25. Haal S, et al. Antibiotic Therapy of 3 Days May Be Sufficient After Biliary Drainage for
Acute Cholangitis: A Systematic Review. Dig Dis Sci. 2021. 66(12):4128-4139.
36
37
26. Tinusz B, et al. Short-Course Antibiotic Treatment Is Not Inferior to a Long-Course One
in Acute Cholangitis: A Systematic Review. Dig Dis Sci. 2019. 64(2):307-315.
38
39
27. Sawyer RG, et al. Trial of short-course antimicrobial therapy for intraabdominal infection.
N Engl J Med. 2015. 372(21):1996-2005.
40
41
42
28. Solomkin JS, et al. Diagnosis and management of complicated intra-abdominal infection
in adults and children: guidelines by the Surgical Infection Society and the Infectious
Diseases Society of America. Clin Infect Dis. 2010. 50(2):133-164.
43
44
45
29. Molina J, et al. Seven-versus 14-day course of antibiotics for the treatment of
bloodstream infections by enterobacterales: a randomized, controlled trial: authors'
response. Clin Microbiol Infect. 2022. 28(5):739-740.
52