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【参考資料２－２】抗微生物薬適正使用の手引き 第四版（案）医科・入院編 (44 ページ)
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抗微生物薬適正使用の手引き
第四版
医科・入院編
1
2
3
70. Yahav D, et al. Bacteremia Duration Study Group. Seven Versus 14 Days of Antibiotic
Therapy for Uncomplicated Gram-negative Bacteremia: A Noninferiority Randomized
Controlled Trial. Clin Infect Dis. 2019. 69(7):1091-1098.
4
5
71. Vento S, et al. Lung infections after cancer chemotherapy. Lancet Oncol. 2008.
9(10):982-992.
6
7
72. Rolston KVI. Infections in Cancer Patients with Solid Tumors: A Review. Infect Dis Ther.
2017. 6(1):69-83.
8
9
73. Geerlings ES. Clinical Presentations and Epidemiology of Urinary Tract Infections.
Microbiol Spectr. 2016. 4(5)
10
11
74. Lipsky AB, et al. Treatment of bacterial prostatitis, Clin Infect Dis. 2010. 50(12):16411652.
12
13
14
75. Kalil CA, et al. Management of Adults With Hospital-acquired and Ventilator-associated
Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of
America and the American Thoracic Society. Clin Infect Dis. 2016. 63(5):e61-111.
15
16
17
76. Bouglé A, et al. Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas
aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, openlabel trial. Intensive Care Med. 2022. 48(7):841-849.
18
19
20
77. Pappas PG, et al. Clinical Practice Guideline for the Management of Candidiasis: 2016
Update by the Infectious Diseases Society of America. Clin Infect Dis. 2016. 62(4):e150.
21
22
23
78. Baddour LM, et al. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy,
and Management of Complications: A Scientific Statement for Healthcare Professionals
From the American Heart Association. Circulation. 2015. 132(15):1435-1486.
24
25
79. Klompas M. Set a short course but follow the patient’s course for ventilator-associated
pneumonia. Chest. 2013. 144(6):1745-1747.
26
27
28
80. Yahav D, et al. Seven Versus 14 Days of Antibiotic Therapy for Uncomplicated Gramnegative Bacteremia: A Noninferiority Randomized Controlled Trial. Clin Infect Dis. 2019.
69(7):1091-1098.
29
30
31
32
81. Dach VE, et al. Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day
Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With
Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial. JAMA. 2020.
323(21):2160-2169.
33
34
35
82. Molina J, et al. Seven-versus 14-day course of antibiotics for the treatment of
bloodstream infections by Enterobacterales: a randomized, controlled trial. Clin Microbiol
Infect. 2022. 28(4):550-557.
36
37
38
83. Turjeman A, et al. Duration of antibiotic treatment for Gram-negative bacteremia –
Systematic review and individual participant data (IPD) meta-analysis.
EClinicalMedicine. 2022. 55:101750.
39
40
84. Cosgrove ES, et al. Management of methicillin-resistant Staphylococcus aureus
bacteremia, Clin Infect Dis. 2008. 46(5):S386-393.
41
42
43
85. Liu C, et al. Clinical practice guidelines by the infectious diseases society of america for
the treatment of methicillin-resistant Staphylococcus aureus infections in adults and
children. Clin Infect Dis. 2011. 52(3):e18-55.
44
45
46
86. Heil LE, et al. Optimizing the Management of Uncomplicated Gram-Negative
Bloodstream Infections: Consensus Guidance Using a Modified Delphi Process. Open
Forum Infect Dis. 2021. 8(10):ofab434.
44
第四版
医科・入院編
1
2
3
70. Yahav D, et al. Bacteremia Duration Study Group. Seven Versus 14 Days of Antibiotic
Therapy for Uncomplicated Gram-negative Bacteremia: A Noninferiority Randomized
Controlled Trial. Clin Infect Dis. 2019. 69(7):1091-1098.
4
5
71. Vento S, et al. Lung infections after cancer chemotherapy. Lancet Oncol. 2008.
9(10):982-992.
6
7
72. Rolston KVI. Infections in Cancer Patients with Solid Tumors: A Review. Infect Dis Ther.
2017. 6(1):69-83.
8
9
73. Geerlings ES. Clinical Presentations and Epidemiology of Urinary Tract Infections.
Microbiol Spectr. 2016. 4(5)
10
11
74. Lipsky AB, et al. Treatment of bacterial prostatitis, Clin Infect Dis. 2010. 50(12):16411652.
12
13
14
75. Kalil CA, et al. Management of Adults With Hospital-acquired and Ventilator-associated
Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of
America and the American Thoracic Society. Clin Infect Dis. 2016. 63(5):e61-111.
15
16
17
76. Bouglé A, et al. Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas
aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, openlabel trial. Intensive Care Med. 2022. 48(7):841-849.
18
19
20
77. Pappas PG, et al. Clinical Practice Guideline for the Management of Candidiasis: 2016
Update by the Infectious Diseases Society of America. Clin Infect Dis. 2016. 62(4):e150.
21
22
23
78. Baddour LM, et al. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy,
and Management of Complications: A Scientific Statement for Healthcare Professionals
From the American Heart Association. Circulation. 2015. 132(15):1435-1486.
24
25
79. Klompas M. Set a short course but follow the patient’s course for ventilator-associated
pneumonia. Chest. 2013. 144(6):1745-1747.
26
27
28
80. Yahav D, et al. Seven Versus 14 Days of Antibiotic Therapy for Uncomplicated Gramnegative Bacteremia: A Noninferiority Randomized Controlled Trial. Clin Infect Dis. 2019.
69(7):1091-1098.
29
30
31
32
81. Dach VE, et al. Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day
Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With
Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial. JAMA. 2020.
323(21):2160-2169.
33
34
35
82. Molina J, et al. Seven-versus 14-day course of antibiotics for the treatment of
bloodstream infections by Enterobacterales: a randomized, controlled trial. Clin Microbiol
Infect. 2022. 28(4):550-557.
36
37
38
83. Turjeman A, et al. Duration of antibiotic treatment for Gram-negative bacteremia –
Systematic review and individual participant data (IPD) meta-analysis.
EClinicalMedicine. 2022. 55:101750.
39
40
84. Cosgrove ES, et al. Management of methicillin-resistant Staphylococcus aureus
bacteremia, Clin Infect Dis. 2008. 46(5):S386-393.
41
42
43
85. Liu C, et al. Clinical practice guidelines by the infectious diseases society of america for
the treatment of methicillin-resistant Staphylococcus aureus infections in adults and
children. Clin Infect Dis. 2011. 52(3):e18-55.
44
45
46
86. Heil LE, et al. Optimizing the Management of Uncomplicated Gram-Negative
Bloodstream Infections: Consensus Guidance Using a Modified Delphi Process. Open
Forum Infect Dis. 2021. 8(10):ofab434.
44