よむ、つかう、まなぶ。
腸内細菌は樹状細胞を介して腸から離れたがんの免疫環境に影響する 免疫チェックポイント阻害薬の作用に関与する新たな腸内細菌を同定 (9 ページ)
出典
| 公開元URL | https://www.ncc.go.jp/jp/information/pr_release/2025/0715/index.html |
| 出典情報 | 国立がん研究センター プレスリリース（7／15）《国立がん研究センター》 |
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タイトル： Microbiota-driven antitumour immunity mediated by dendritic cell migration
著者:
Nina Yi-Tzu Lin1,2,*, Shota Fukuoka1,*, Shohei Koyama1,3,*, Daisuke Motooka4,
Dieter M. Tourlousse5, Yuko Shigeno6, Yuki Matsumoto4, Hiroyuki Yamano4,
Kazutoshi Murotomi5, Hideyuki Tamaki7, Takuma Irie1, Eri Sugiyama1,8,
Shogo Kumagai1,9, Kota Itahashi1, Tokiyoshi Tanegashima1, Kaori Fujimaki2,
Sachiko Ito2, Mariko Shindo10, Takahiro Tsuji10, Hiroaki Wake10, Keisuke Watanabe1,
Yuka Maeda1, Tomohiro Enokida11, Makoto Tahara11, Riu Yamashita12,
Takao Fujisawa11,13, Motoo Nomura14, Akihito Kawazoe15, Koichi Goto8,
Toshihiko Doi15, Kohei Shitara15, Hiroyuki Mano9, Yuji Sekiguchi5, Shota Nakamura4,
Yoshimi Benno6,16,#, Hiroyoshi Nishikawa1,2,17,18,#,
＋
所属:
1Division of Cancer Immunology, Research Institute/Exploratory Oncology Research &
Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577,
Japan
2Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya
466-8550, Japan
3Department of Respiratory Medicine and Clinical Immunology, The University of Osaka
Graduate School of Medicine, Osaka 565-0871, Japan
4Department of Infection Metagenomics, Genome Information Research Center,
Research Institute for Microbial Diseases, The University of Osaka, Osaka 565-0871,
Japan
5Molecular Biosystems Research Institute, National Institute of Advanced Industrial
Science and Technology (AIST), Ibaraki 305-8566, Japan
6Benno Laboratory, RIKEN Baton Zone Program, RIKEN Cluster for Science
Technology and Innovation Lab, Saitama 351-0198, Japan
7Biomanufacturing Process Research Center, National Institute of Advanced Industrial
Science and Technology (AIST), Ibaraki 305-8566, Japan
8Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba 277-
8577, Japan
9Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo 104-
0045, Japan
10Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate
School of Medicine, Nagoya 466-8550, Japan
11Department of Head and Neck Medical Oncology, National Cancer Center Hospital
East, Chiba 277-8577, Japan
12Division of Translational Informatics, Exploratory Oncology Research & Clinical Trial
Center (EPOC), National Cancer Center, Chiba 277-8577, Japan
13Translational Research Support Office, National Cancer Center Hospital East, Chiba
277-8577, Japan
9
著者:
Nina Yi-Tzu Lin1,2,*, Shota Fukuoka1,*, Shohei Koyama1,3,*, Daisuke Motooka4,
Dieter M. Tourlousse5, Yuko Shigeno6, Yuki Matsumoto4, Hiroyuki Yamano4,
Kazutoshi Murotomi5, Hideyuki Tamaki7, Takuma Irie1, Eri Sugiyama1,8,
Shogo Kumagai1,9, Kota Itahashi1, Tokiyoshi Tanegashima1, Kaori Fujimaki2,
Sachiko Ito2, Mariko Shindo10, Takahiro Tsuji10, Hiroaki Wake10, Keisuke Watanabe1,
Yuka Maeda1, Tomohiro Enokida11, Makoto Tahara11, Riu Yamashita12,
Takao Fujisawa11,13, Motoo Nomura14, Akihito Kawazoe15, Koichi Goto8,
Toshihiko Doi15, Kohei Shitara15, Hiroyuki Mano9, Yuji Sekiguchi5, Shota Nakamura4,
Yoshimi Benno6,16,#, Hiroyoshi Nishikawa1,2,17,18,#,
＋
所属:
1Division of Cancer Immunology, Research Institute/Exploratory Oncology Research &
Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577,
Japan
2Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya
466-8550, Japan
3Department of Respiratory Medicine and Clinical Immunology, The University of Osaka
Graduate School of Medicine, Osaka 565-0871, Japan
4Department of Infection Metagenomics, Genome Information Research Center,
Research Institute for Microbial Diseases, The University of Osaka, Osaka 565-0871,
Japan
5Molecular Biosystems Research Institute, National Institute of Advanced Industrial
Science and Technology (AIST), Ibaraki 305-8566, Japan
6Benno Laboratory, RIKEN Baton Zone Program, RIKEN Cluster for Science
Technology and Innovation Lab, Saitama 351-0198, Japan
7Biomanufacturing Process Research Center, National Institute of Advanced Industrial
Science and Technology (AIST), Ibaraki 305-8566, Japan
8Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba 277-
8577, Japan
9Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo 104-
0045, Japan
10Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate
School of Medicine, Nagoya 466-8550, Japan
11Department of Head and Neck Medical Oncology, National Cancer Center Hospital
East, Chiba 277-8577, Japan
12Division of Translational Informatics, Exploratory Oncology Research & Clinical Trial
Center (EPOC), National Cancer Center, Chiba 277-8577, Japan
13Translational Research Support Office, National Cancer Center Hospital East, Chiba
277-8577, Japan
9