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資料３－４ 研究報告の報告状況 (10 ページ)
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研究報告の報告状況
（2022年8月1日～2022年11月30日）
NO
一般名
文献名
Brahim Azzouz. Psoriasis risk after beta-blocker exposure:Description of a
チモロールマレイン酸塩
229
pharmacovigilance signal. British Journal of Clinical Pharmacology. 2022; 88(8): 3813ドルゾラミド塩酸塩・チモロールマレイン酸塩
3818.
Hideo Fukuhara.Identification of risk factors associated with oral 5-aminolevulinic acid230 アミノレブリン酸塩酸塩
induced hypotension in photodynamic diagnosis for non-muscle invasive bladder cancer: a
multicenter retrospective study.BMC Cancer (2021) 21:1223
Smith IO, et al. Concerns about safety of growth hormone therapy in noonan syndrome
ソマトロピン（遺伝子組換え）
231
and other rasopathies: Risk of triggering or worsening hypertrophic cardiomyopathy.
ソマプシタン（遺伝子組換え）
Cardiology in the Young, suppl. Supplement 232: S258 (2022)
Jean-Luc Faillie, Hui Yin, Oriana H. Y. Yu, Astrid Herrero, Romain Altwegg, Christel
Renoux and Laurent Azoulay. Incretin-Based Drugs and Risk of Intestinal Obstruction
232 サキサグリプチン水和物
Among Patients With Type 2 Diabetes. CLINICAL PHARMACOLOGY &
THERAPEUTICS. 2022;111
Ghadeer K. Dawwas , Sean Hennessy, Colleen M. Brensinger, Rajat Deo ,Warren B.
Bilker, Samantha E. Soprano, Neil Dhopeshwarkar , James H. Flory,Zachary T.
233 サキサグリプチン水和物
Bloomgarden, Christina L. Aquilante, Stephen. Comparative safety of dipeptidyl
peptidase-4 inhibitors and sudden cardiac arrest and ventricular arrhythmia: populationbased cohort studies. CLINICAL PHARMACOLOGY & THERAPEUTICS. 2022;111
Loukovaara, S. et al. Associations between systemic medications and development of wet
234 バルサルタン・アムロジピンベシル酸塩配合剤
age-related macular degeneration.
Acta Ophthalmol. 2022;100(5):572-582.
Williamson SJ, Plant ND, Shenoy M. Use of normal saline and incidence of
235 生理食塩液
dyselectrolytaemia in children following kidney transplantation. Pediatr-Nephrol.
2022;37(9):2127-2130
アテノロール
Sorbye, I.K. et al. .Maternal beta-blocker dose and risk of small-for gestational-age in
236
メトプロロール酒石酸塩
women with heart disease.Acta Obstet. Gynecol. Scand. 2022;101(7):794-802.
Loukovaara, S. et al.. Associations between systemic medications and development of wet
237 アトルバスタチンカルシウム水和物
age-related macular degeneration. Acta Ophthalmol.. 2022; 100(5): 572-582.
エトドラク
Leonie S. Penner. Does coprescribing nonsteroidal anti-inflammatory drugs and oral
238 ロキソプロフェンナトリウム水和物
anticoagulants increase the risk of major bleeding, stroke and systemic embolism?. Br. J.
ブコローム
Clin. Pharmacol.. 2022; 88(11): 4789-4811.
Xian Qin, Keng PoLai, Rudolf Shiu Sun Wu, Richard Yuen Chong Kong. Continuous
239 デソゲストレル・エチニルエストラジオール
17.alpha.-ethinylestradiol exposure impairs the sperm quality of marine medaka (Oryzias
melastigma).. Marine Pollution Bulletin. 2022;183:114093
Edouard, L.. A history of variceal bleeding is associated with further bleeding under
240 ベバシズマブ（遺伝子組換え）［後続１］
Atezolizumab-Bevacizumab in patients with HCC. Liver international : official journal
of the International Association. 2022
Luke B. Allen, Karoly Mirnics.Metoprolol Inhibits Developmental Brain Sterol
241 メトプロロール酒石酸塩
Biosynthesis in Mice.Biomolecules.12(9):1-16
Shi X, et al..Effects of antiepileptic drugs polytherapy on pregnancy outcomes in women
プロキシフィリン・エフェドリン塩酸塩・フェノバルビタール配合
242
with epilepsy: An observation study in northwest China..Epilepsy and Behavior
剤
2022;135:108904(Article #).
Kalk NJ, et al. Fatalities associated with gabapentinoids in England (2004-2020). Br J Clin
243 トラマドール塩酸塩・アセトアミノフェン配合剤
Pharmacol. 2022; 88(8): 3911-3917.
Patrick S. Creisher et al. Influenza subtype-specific maternal antibodies protect offspring
244 インフルエンザＨＡワクチン
against infection but inhibit vaccine-induced immunity and protection in mice. Vaccine
2022. doi:10.1016/j.vaccine.2022.10.003
Zolpidem use and risk of suicide: A systematic review and meta-analysis.
Khan H, et al. Centre for Translational & Clinical Research, School of Chemical and Life
245 ゾルピデム酒石酸塩
Sciences, Jamia Hamdard, New Delhi 110062, India.
Psychiatry research 316巻､114777頁､2022年
Yamashiro K, Jouta M, Hosomi K, Yokoyama S, Ozaki Y, Hirata A, et al. Adverse event
246 ニコランジル
profiles of microscopic colitis in the Japanese Adverse Drug Event Report (JADER)
database. Scientific reports. 2022;12:17652-17659
Charles-Schoeman, C.. Risk of major adverse cardiovascular events with tofacitinib versus
tumour necrosis factor inhibitors in patients with rheumatoid arthritis with or without a
247 トファシチニブクエン酸塩
history of atherosclerotic cardiovascular disease: a post hoc analysis from ORAL
Surveillance. CLINICAL SCIENCE. 2022
Kantisin, Siriwan.In utero arsenic exposure increases DNA damage and gene expression
248 三酸化二ヒ素
changes in umbilical cord mesenchymal stem cells (UC-MSCs) from newborns as well as in
UC-MSC differentiated hepatocytes..Toxicology Reports 2022;9:1728-1741.
Khosro-khavar, F.. Tofacitinib and Risk of Malignancy: Results From the Safety of
249 トファシチニブクエン酸塩
Tofacitinib in Routine Care Patients With Rheumatoid Arthritis (STAR-RA) Study.
CLINICAL SCIENCE. 2022
Islam, N. et al. Sulfonylureas and the risk of ventricular arrhythmias among people with
250 グリメピリド
type 2 diabetes: A systematic review of observational studies. Clin. Pharmacol. Ther.
2022, 111(6), 1248-1257
Wang Y, et al. Intraoperative low-dose dopamine is associated with worse survival in
251 ドパミン塩酸塩
patients with hepatocellular carcinoma: A propensity score matching analysis. Frontiers in
Oncology. 2022;12:947172
Kim JE, et al.. Associations of Guillain-Barre syndrome with coronavirus disease 2019
コロナウイルス（ＳＡＲＳ－ＣｏＶ－２）ワクチン（遺伝子組換え vaccination: Disproportionality analysis using the World Health Organization
252
サルアデノウイルスベクター）
pharmacovigilance database.. Journal of the Peripheral Nervous System 2022; 27(3): 206214.
Cicek A, et al.. Effect of pupil dilation on intraocular pressure in preterm and term
253 トロピカミド・フェニレフリン塩酸塩
infants.. Arq Bras Oftalmol. 2022; 85(5): 485-489.
Unique properities of depressor, renal and aldosterone responses to aliskiren therapy in
254 アリスキレンフマル酸塩
hypertensive patients with nephropathy
Jin, X.-L. et al.
Neonatal outcomes after gamma-aminobutyric acid analog use during pregnancy: a meta255 プレガバリン
analysis of cohort studies
Europ. J. Clin. Pharmacol. 2022, 78(11), 1739-1747
10
（2022年8月1日～2022年11月30日）
NO
一般名
文献名
Brahim Azzouz. Psoriasis risk after beta-blocker exposure:Description of a
チモロールマレイン酸塩
229
pharmacovigilance signal. British Journal of Clinical Pharmacology. 2022; 88(8): 3813ドルゾラミド塩酸塩・チモロールマレイン酸塩
3818.
Hideo Fukuhara.Identification of risk factors associated with oral 5-aminolevulinic acid230 アミノレブリン酸塩酸塩
induced hypotension in photodynamic diagnosis for non-muscle invasive bladder cancer: a
multicenter retrospective study.BMC Cancer (2021) 21:1223
Smith IO, et al. Concerns about safety of growth hormone therapy in noonan syndrome
ソマトロピン（遺伝子組換え）
231
and other rasopathies: Risk of triggering or worsening hypertrophic cardiomyopathy.
ソマプシタン（遺伝子組換え）
Cardiology in the Young, suppl. Supplement 232: S258 (2022)
Jean-Luc Faillie, Hui Yin, Oriana H. Y. Yu, Astrid Herrero, Romain Altwegg, Christel
Renoux and Laurent Azoulay. Incretin-Based Drugs and Risk of Intestinal Obstruction
232 サキサグリプチン水和物
Among Patients With Type 2 Diabetes. CLINICAL PHARMACOLOGY &
THERAPEUTICS. 2022;111
Ghadeer K. Dawwas , Sean Hennessy, Colleen M. Brensinger, Rajat Deo ,Warren B.
Bilker, Samantha E. Soprano, Neil Dhopeshwarkar , James H. Flory,Zachary T.
233 サキサグリプチン水和物
Bloomgarden, Christina L. Aquilante, Stephen. Comparative safety of dipeptidyl
peptidase-4 inhibitors and sudden cardiac arrest and ventricular arrhythmia: populationbased cohort studies. CLINICAL PHARMACOLOGY & THERAPEUTICS. 2022;111
Loukovaara, S. et al. Associations between systemic medications and development of wet
234 バルサルタン・アムロジピンベシル酸塩配合剤
age-related macular degeneration.
Acta Ophthalmol. 2022;100(5):572-582.
Williamson SJ, Plant ND, Shenoy M. Use of normal saline and incidence of
235 生理食塩液
dyselectrolytaemia in children following kidney transplantation. Pediatr-Nephrol.
2022;37(9):2127-2130
アテノロール
Sorbye, I.K. et al. .Maternal beta-blocker dose and risk of small-for gestational-age in
236
メトプロロール酒石酸塩
women with heart disease.Acta Obstet. Gynecol. Scand. 2022;101(7):794-802.
Loukovaara, S. et al.. Associations between systemic medications and development of wet
237 アトルバスタチンカルシウム水和物
age-related macular degeneration. Acta Ophthalmol.. 2022; 100(5): 572-582.
エトドラク
Leonie S. Penner. Does coprescribing nonsteroidal anti-inflammatory drugs and oral
238 ロキソプロフェンナトリウム水和物
anticoagulants increase the risk of major bleeding, stroke and systemic embolism?. Br. J.
ブコローム
Clin. Pharmacol.. 2022; 88(11): 4789-4811.
Xian Qin, Keng PoLai, Rudolf Shiu Sun Wu, Richard Yuen Chong Kong. Continuous
239 デソゲストレル・エチニルエストラジオール
17.alpha.-ethinylestradiol exposure impairs the sperm quality of marine medaka (Oryzias
melastigma).. Marine Pollution Bulletin. 2022;183:114093
Edouard, L.. A history of variceal bleeding is associated with further bleeding under
240 ベバシズマブ（遺伝子組換え）［後続１］
Atezolizumab-Bevacizumab in patients with HCC. Liver international : official journal
of the International Association. 2022
Luke B. Allen, Karoly Mirnics.Metoprolol Inhibits Developmental Brain Sterol
241 メトプロロール酒石酸塩
Biosynthesis in Mice.Biomolecules.12(9):1-16
Shi X, et al..Effects of antiepileptic drugs polytherapy on pregnancy outcomes in women
プロキシフィリン・エフェドリン塩酸塩・フェノバルビタール配合
242
with epilepsy: An observation study in northwest China..Epilepsy and Behavior
剤
2022;135:108904(Article #).
Kalk NJ, et al. Fatalities associated with gabapentinoids in England (2004-2020). Br J Clin
243 トラマドール塩酸塩・アセトアミノフェン配合剤
Pharmacol. 2022; 88(8): 3911-3917.
Patrick S. Creisher et al. Influenza subtype-specific maternal antibodies protect offspring
244 インフルエンザＨＡワクチン
against infection but inhibit vaccine-induced immunity and protection in mice. Vaccine
2022. doi:10.1016/j.vaccine.2022.10.003
Zolpidem use and risk of suicide: A systematic review and meta-analysis.
Khan H, et al. Centre for Translational & Clinical Research, School of Chemical and Life
245 ゾルピデム酒石酸塩
Sciences, Jamia Hamdard, New Delhi 110062, India.
Psychiatry research 316巻､114777頁､2022年
Yamashiro K, Jouta M, Hosomi K, Yokoyama S, Ozaki Y, Hirata A, et al. Adverse event
246 ニコランジル
profiles of microscopic colitis in the Japanese Adverse Drug Event Report (JADER)
database. Scientific reports. 2022;12:17652-17659
Charles-Schoeman, C.. Risk of major adverse cardiovascular events with tofacitinib versus
tumour necrosis factor inhibitors in patients with rheumatoid arthritis with or without a
247 トファシチニブクエン酸塩
history of atherosclerotic cardiovascular disease: a post hoc analysis from ORAL
Surveillance. CLINICAL SCIENCE. 2022
Kantisin, Siriwan.In utero arsenic exposure increases DNA damage and gene expression
248 三酸化二ヒ素
changes in umbilical cord mesenchymal stem cells (UC-MSCs) from newborns as well as in
UC-MSC differentiated hepatocytes..Toxicology Reports 2022;9:1728-1741.
Khosro-khavar, F.. Tofacitinib and Risk of Malignancy: Results From the Safety of
249 トファシチニブクエン酸塩
Tofacitinib in Routine Care Patients With Rheumatoid Arthritis (STAR-RA) Study.
CLINICAL SCIENCE. 2022
Islam, N. et al. Sulfonylureas and the risk of ventricular arrhythmias among people with
250 グリメピリド
type 2 diabetes: A systematic review of observational studies. Clin. Pharmacol. Ther.
2022, 111(6), 1248-1257
Wang Y, et al. Intraoperative low-dose dopamine is associated with worse survival in
251 ドパミン塩酸塩
patients with hepatocellular carcinoma: A propensity score matching analysis. Frontiers in
Oncology. 2022;12:947172
Kim JE, et al.. Associations of Guillain-Barre syndrome with coronavirus disease 2019
コロナウイルス（ＳＡＲＳ－ＣｏＶ－２）ワクチン（遺伝子組換え vaccination: Disproportionality analysis using the World Health Organization
252
サルアデノウイルスベクター）
pharmacovigilance database.. Journal of the Peripheral Nervous System 2022; 27(3): 206214.
Cicek A, et al.. Effect of pupil dilation on intraocular pressure in preterm and term
253 トロピカミド・フェニレフリン塩酸塩
infants.. Arq Bras Oftalmol. 2022; 85(5): 485-489.
Unique properities of depressor, renal and aldosterone responses to aliskiren therapy in
254 アリスキレンフマル酸塩
hypertensive patients with nephropathy
Jin, X.-L. et al.
Neonatal outcomes after gamma-aminobutyric acid analog use during pregnancy: a meta255 プレガバリン
analysis of cohort studies
Europ. J. Clin. Pharmacol. 2022, 78(11), 1739-1747
10